Caliac Disease

Find out if you are affected

What is Celiac Disease?

Celiac Disease is a hereditary intestinal disease.
Intestinal mucosal damage, and even immune disorders, can be complicated by many different symptoms,
Increasing the risk of developing other autoimmune diseases!

Hardly Noticeable!

Those diagnosed with celiac disease are like only the tip of the iceberg.
Many people are suffering from damaged intestine mucosal,
however since the symptoms are not obvious, they do not know they are being affected！

Intrinsic factor：genetics

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Protein of gluten damage the intestine mucosa

Appearance of typical intestinal symptoms and malabsorption

Concurrent with other symptoms and increase the risk of other autoimmune diseases

Extrinsic factor：

presence of gluten

Symptoms of Celiac Disease

TYPICAL & CLASSIC SYMPTOMS

Chronic diarrhea,
Failure to thrive,
Abdominal distention

ATYPICAL SYMPTOMS

(SECONDARY TO MALABSORPTION)

Sideropenic anemia,

Short stature,

Osteopenia, Recurrent abortions,Hepatic steatosis, Recurrent abdominal pain,Gaseousness

ATYPICAL SYMPTOMS

(INDEPENDENT OF MALADSORPTION)

Dermatitis herpetiformis, Dental enamel hypoplasia, Ataxia, Alopecia,
Primary biliary cirrhosis,
Isolated hypertransaminasemia,
Recurrent aphthous stomatitis,
Myasthenia gravis, Recurrent pericarditis,
Psoriasis, Dental enamel hypoplasia,
Epilepsy (with or without intracranial calcifications),
Vasculitis, Dilatative cardiomyopathy,
Hypo/Hyperthyroidism

Source: American Society of Gastroenterology

What are gluten and gliadin?

Gluten is a general name for the proteins found in wheat (varieties of wheat include: durum, emmer, spelt, farina, farro, kamut and einkorn), rye, barley and triticale.

Gliadin is one of the main protein components in gluten. The test is used to help find out whether you have celiac disease, an autoimmune disease by looking at the reaction to Gliadin.

Why we need to choose blood test?

Research studies have shown that the combination of tTG and DGP can detect nearly all biopsy proven celiac patients.

According to American Gastroenterological Association (AGA), blood test is a less invasive and easier method, compared to upper endoscopy and intestinal biopsy. It reduces discomfort and lesions caused by these invasive methods.

HK BioTek Technology Competency

• Each sample will be tested in duplicate to ensure quality
• US Food and Drug Administration (FDA)-approved INOVA QUANTA Flash® CIA immunoassay technology with high sensitivity and specificity
• CIA significantly increases the analytical measuring range, allowing the practitioner to monitor gluten-free diet compliance

Test Items

ANTIGENS

Tissue transglutaminase (tTG)

Deamidated gliadin peptide (DGP)

ANTIGENS

IgA-tTG

IgG-tTG

IgA-DGP

The Testing Process

Sample Report

User Testimonials

Before Deciding on a Gluten Free Diet

Gastroenterologist, Hong Kong

“This test covers almost everything I want to see when I suspect a patient may have celiac disease, before asking them going for a gluten free diet.”

IgG positive

Nutritionist, Hong Kong

“When patient is found to be IgG positive to wheat and suffering from celiac-like symptoms, I order this test to screen if the patient is a celiac. This is very helpful as the result tells if the patient needs to avoid gluten just a period of time or in the lifetime.”

Just Gluten-Intolerant

Mr. JF, Hong Kong

“Going gluten-free is a trend in Hong Kong and USA. I do feel better after cutting gluten in my diet, yet I still want to confirm if I am a celiac, this’s why I ordered this test. The result has shown that I am just gluten-intolerant but not a celiac.”

Frequently-Asked Questions

1. What are the benefits of the Celiac Screening?

• Report shows exact values for four markers (IgA-and IgG-tTG, IgA-and IgG-DGP) and a reference value will be provided.
• A small amount of blood via blood drawing is required
• Analysis completed in the U.S.
• Comprehensive supporting information in client information sheets

2. Why shall I choose blood test for Celiac Disease?

Blood test is a very convenient and less invasive method, compared to upper endoscopy and intestinal biopsy. Using blood test can reduce the discomfort and lesions caused by those invasive methods. IgA-and IgG-tTG, IgA-and IgA-DGP tests constitute valuable diagnostic tools in the decision for more invasive intestinal biopsy. Also, they have proven their value of for the follow-up of CD and have revealed the high prevalence of undiagnosed CD. Therefore, scientific journals and medical organizations suggest that rather than ordering invasive testing, it is far better to start with serological testing on some reliable markers and follow up as necessary

3. Can the Celiac Screening test provide accurate and reliable test results?

HK BioTek's celiac test uses blood samples for testing. Through INOVA QUANTA Flash® CIA immunoassay technology, we are able to analyze the levels of IgA- and IgG-tTG, as well as IgA- and IgG-DGP antibodies in the blood to give positive or negative results. The combination of test results and other clinical observations will help you and your healthcare professional to find out more about your condition. In patients with celiac disease, the damaged intestines will fully recover after all gluten foods have been withdrawn.

All blood samples are sent to US BioTek Labs for testing, and each sample is retested to ensure accuracy, and the test is approved by the US Food and Drug Administration (FDA). Authorized by the Commission on Office Laboratory Accreditation (COLA), US BioTek Labs is the only laboratory with reproducible results that is the most sensitive to blood samples.